Dr. Joel Fleischman (Rob Morrow) is fresh out of medical college, and fresh out of luck. Failing to read the fine print in his scholarship conditions, he finds he has no choice but to move to the remote and somewhat eccentric town of Cicely, Alaska. Once there, he is welcomed by the peculiar locals who are not keen to see him go, most especially Maurice J. Minnifield (Barry Corbin), the ex-N.A.S.A. astronaut. Despite Joel's adamant denials, one gets the impression that he enjoys life in Cicely more than he admits.