Eli Lilly Invests in Pennsylvania to Build a New Manufacturing Site
- Jan 30
- 2 min read

Pharmaceutical giant Eli Lilly announced on Friday its plans to invest $3.5 billion to construct a state-of-the-art manufacturing facility in Fogelsville, Pennsylvania. This new site, located in the Lehigh Valley, is dedicated to the production of next-generation obesity injections and medical devices.
The facility is the fourth major domestic investment announced by the company in the last year, completing a "quartet" of new U.S. plants that include sites in Virginia, Texas, and Alabama. These expansions are part of a broader $27 billion commitment to boost domestic manufacturing capacity.
The Pennsylvania plant will primarily focus on retatrutide, an experimental "triple-hormone" drug that has demonstrated the highest weight loss of any treatment seen to date in late-stage clinical trials. By targeting three gut hormones instead of one or two, health experts believe retatrutide could provide a critical option for patients with severe obesity who require more significant weight loss than current treatments offer.
The project is expected to bring 850 high-quality jobs to the region, including roles for scientists, engineers, and lab technicians, alongside approximately 2,000 construction jobs. Governor Josh Shapiro noted that Pennsylvania is committing $100 million to the project, which represents the largest life sciences investment in the state's history.
The push for domestic production follows threats of pharmaceutical import tariffs by the Trump administration. While Lilly and other drugmakers recently reached pricing deals to exempt them from these levies for three years, the strategic move toward U.S.-based manufacturing ensures a more resilient medical supply chain.
Lilly is currently in a fierce race with rival Novo Nordisk to dominate the booming GLP-1 market. While Lilly secured the majority market share last year, both companies are investing heavily to resolve previous supply shortages. Construction on the Lehigh Valley site is slated to begin this year, with the facility expected to be fully operational by 2031.
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